Pancreatobiliary FISH
Ordering Recommendation
Detect aneuploidy for chromosomes 3, 7, and 17. Use in conjunction with current standard diagnostic procedures as an aid for diagnosis of pancreatic cancer.
New York DOH Approval Status
Specimen Required
Bile or pancreatic duct brushings, biliary stent, or fine needle aspirates of the pancreas in UroCyte Collection Kit (ARUP Supply #41440) available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787. For specific instructions refer to Specimen Collection & Handling.
Place specimen in Cytolyt or PreservCyt fixative vial. If the specimen is a brushing, submit the brush in the fixative. Specimen should be placed in fixative vial immediately after collection.
Ambient or Refrigerated.
Frozen specimens. Unfixed specimens not collected in Cytolyt or PreservCyt fixative. Specimens submitted in expired collection vials.
Specimen source is required.
Ambient: 1 week from collection; Refrigerated: 1 week from collection; Frozen: Unacceptable
Methodology
Fluorescence in situ Hybridization (FISH)/Computer Assisted Analysis/Microscopy
Performed
Mon-Fri
Reported
4-14 days
Reference Interval
Negative: No evidence of numeric chromosomal aberrations associated with pancreatobiliary carcinoma identified.
Positive: Numeric chromosomal aberrations associated with pancreatobiliary carcinoma identified.
Interpretive Data
Refer to Report.
Laboratory Developed Test (LDT)
Note
Results of this test must be interpreted in conjunction with clinical evidence and other laboratory testing and should not be used alone, as a diagnosis of pancreatobiliary carcinoma.
A positive fluorescence in situ hybridization (FISH) result does not identify location or type of malignancy. FISH abnormalities may be associated with high-grade dysplasia or carcinoma in situ. Cytology and biopsy may help clarify such situations.
Hotline History
Hotline History
CPT Codes
88366
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2002452 | Pancreatobiliary FISH Specimen Source | 66746-9 |
2002458 | Fixative | 8100-0 |
2002459 | Pancreatobiliary FISH Clinical History | 22636-5 |
2002463 | Pancreatobiliary FISH Gross Description | 22634-0 |
Aliases
- Bile Duct FISH
- Bile Duct Tumor
- Biliary Tract Malignancy FISH
- Cholangiocarcinoma FISH
- Cytology
- FISH
- Pancreas FISH