Bence Jones Protein, Quantitation and Characterization, with Reflex to Kappa/Lambda Free Light Chains with Ratio, Urine
Ordering Recommendation

Aids in the workup of plasma cell dyscrasia. Use to detect and quantify urinary free light chains (Bence Jones protein).

Semi-Quantitative Electrophoresis/Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry
Mon, Wed, Fri
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
24-hour urine. Refrigerate during collection. Also acceptable: Random urine specimens and urine supernate. 
Specimen Preparation
Transfer two 4 mL aliquots from well-mixed 24 hour collection to individual ARUP Standard Transport Tubes. (Min: 4 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Non-refrigerated specimens. 
Record total volume and collection time interval on transport tube and test request form. 
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month 
Reference Interval
Test Number
Reference Interval
Total Protein, Urine mg/dL
Total Protein, Urine Excretion mg/dL40-150 mg/dL
Albumin%, Urine%
Alpha-1 Globulins%, Urine%
Alpha-2 Globulins%, Urine%
Beta Globulins%, Urine%
Gamma Globulins%, Urine%
Paraprotein%, Urine%
Paraprotein Excretion mg/dL%
Free Urinary Kappa Light Chains0.14-2.42 mg/dL
Free Urinary Kappa Excretion/Day
Free Urinary Lambda Light Chains0.02-0.67 mg/dL
Free Urinary Lambda Excretion/Day
Free Urinary Kappa/Lambda Ratio2.04-10.37
IFE InterpretationBy report

Interpretive Data

If Paraprotein%, Urine is resulted as trace or with a numeric value, then Kappa and Lambda Free Light Chains, Urine will be added. Additional charges apply.
Hotline History
View Hotline History
CPT Code(s)
84156; 84166; 86335; if reflexed, add 83883 x2
Component Test Code*Component Chart NameLOINC
0020200Total Protein, Urine-per volume2888-6
0020215Urine 24 Hour Protein2889-4
0050688IFE Interpretation13440-3
0097110Total Volume19153-6
0097111Hours Collected30211-7
2002465Paraprotein Excretion/24 Hour42482-0
2002466Alpha-1 %, Urine13984-0
2002467Alpha-2 %, Urine13987-3
2002468Beta Globulin %, Urine13988-1
2002469Gamma Globulin %, Urine13989-9
2002478Albumin %, Urine13986-5
2002490Paraprotein %, Urine42484-6
2012456EER BJProtein Qnt w/Rflx k/l FLC w/Ratio
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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