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Bence Jones Protein, Quantitation and Characterization, with Reflex to Kappa/Lambda Free Light Chains with Ratio, Urine
2002464
Ordering Recommendation

Aids in the workup of plasma cell dyscrasia. Use to detect and quantify urinary free light chains (Bence Jones protein).

Mnemonic
BJP-U REFLEX
Methodology
Semi-Quantitative Electrophoresis/Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry
Performed
Mon, Wed, Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
24-hour urine. Refrigerate during collection. Also acceptable: Random urine specimens and urine supernate. 
Specimen Preparation
Transfer two 4 mL aliquots from well-mixed 24 hour collection to individual ARUP Standard Transport Tubes. (Min: 3 mL) Record total volume and collection time interval on transport tube and test request form. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Non-refrigerated specimens. 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month 
Reference Interval
Test Number
Components
Reference Interval
Total Protein, Urine mg/dL
Total Protein, Urine Excretion mg/dL40-150 mg/dL
Albumin%, Urine%
Alpha-1 Globulins%, Urine%
Alpha-2 Globulins%, Urine%
Beta Globulins%, Urine%
Gamma Globulins%, Urine%
Paraprotein%, Urine%
Paraprotein Excretion mg/dL%
Free Urinary Kappa Light Chains0.14-2.42 mg/dL
Free Urinary Kappa Excretion/Day
Free Urinary Lambda Light Chains0.02-0.67 mg/dL
Free Urinary Lambda Excretion/Day
Free Urinary Kappa/Lambda Ratio2.04-10.37
IFE InterpretationBy report

Interpretive Data


Note
If Paraprotein%, Urine is resulted as trace or with a numeric value, then Kappa and Lambda Free Light Chains, Urine will be added. Additional charges apply.
CPT Code(s)
84156; 84166; 86335; if reflexed, add 83883 x2
Components
Component Test Code*Component Chart NameLOINC
0020200Total Protein, Urine-per volume2888-6
0020215Urine 24 Hour Protein2889-4
0050688IFE Interpretation13440-3
0097110Total Volume19153-6
0097111Hours Collected30211-7
2002465Paraprotein Excretion/24 Hour42482-0
2002466Alpha-1 %, Urine13984-0
2002467Alpha-2 %, Urine13987-3
2002468Beta Globulin %, Urine13988-1
2002469Gamma Globulin %, Urine13989-9
2002478Albumin %, Urine13986-5
2002490Paraprotein %, Urine42484-6
2012456EER BJProtein Qnt w/Rflx k/l FLC w/Ratio
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Electrophoresis and Immunofixation, urine
  • IFE
  • Light Chain Disease Study
  • Monoclonal Protein Study, urine
  • Protein Electrophoresis, Urine
  • Protein Fractionation, urine
  • UEP
  • UPEP
  • Urine IFE
  • Urine Protein Electrophoresis