Ordering Recommendation

Standard of care prior to abacavir therapy per FDA. Predicts risk of abacavir hypersensitivity syndrome. Relevant to most populations.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma or serum. Heparinized specimens. Frozen specimens in glass collection tubes.

Remarks
Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month.

Methodology

Polymerase Chain Reaction/Fluorescence Monitoring

Performed

Varies

Reported

5-10 days

Reference Interval

By report

Interpretive Data

Refer to Report


Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

81381

Components

Component Test Code* Component Chart Name LOINC
2002431 HLA-B*57:01 Specimen 31208-2
2002432 HLA-B*57:01 Allele 50956-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Abacavir hypersensitivity genotyping
  • Abacavir Sensitivity
  • HLA-B 5701 Genotype, Abacavir Hypersensitivity, Saliva
HLA-B*57:01 for Abacavir Sensitivity