Chromosome FISH, Interphase
2002298
Ordering Recommendation
 
Mnemonic
CHR FISHI
Methodology
Fluorescence in situ Hybridization
Performed
Sun-Sat
Reported
3-10 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Time SensitiveTime Sensitive

Oncology Test Request Form Recommended (ARUP form #43099)Oncology Test Request Form Recommended (ARUP form #43099)

Specimen Required
Patient Preparation
  
Collect
Non-diluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Green (sodium heparin).  
Specimen Preparation
Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL). OR transport 5 mL whole blood (Min: 2 mL)  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Frozen specimens. Paraffin-embedded specimens. Clotted specimens.  
Remarks
  
Stability
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
By report  
Interpretive Data


See Compliance Statement A: www.aruplab.com/CS
Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.
 
Note
Time required for testing can vary depending on specimen type and probes ordered.

Please indicate the names of probes needed for testing. Molecular Cytogenetics (FISH) Probe menu is available at http://www.aruplab.com/Testing-Information/resources/FISH_probes/fish_probes_oncology.pdf
Contact ARUP Genetics Processing at extension 3301 to add a probe to a current specimen.

Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.

If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.

This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
CPT Code(s)
88271; 88275; 88291
Components
Component Test Code*Component Chart Name
0092615Chromosome FISH, Interphase
2002196EER Chromosome FISH, Interphase
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • +12
  • +4, +10, +17 Panel
  • +8
  • 11q23
  • 14q32
  • 18q11.2
  • 19p13
  • 20q Deletion (D20S108)
  • 22q12.2
  • 3q27
  • 4q12
  • 5q Deletion (EGR1)/Monosomy 5
  • 5q32
  • 5q33.1
  • 7q Deletion(D7S486)/Monosomy 07
  • 8p12
  • 8q24
  • 9p21
  • ATM Deletion
  • BCL6 Rearrangement
  • C-Myc (MYC) Rearrangement
  • Cancer FISH
  • CBFB
  • CBFB Rearrangement
  • D13S319 Deletion
  • Del(11)(q22.3)
  • Del(13)(q14.3)
  • Del(17)(p13.1) (TP53) Deletion
  • Del(20)(q12)
  • Del(5)(q31)/-5
  • Del(7)(q31)/-7
  • EVT6-RUNX1 (TEL-AML1 ) Fusion
  • EWSR1 Rearrangement
  • FGFR1 Rearrangement
  • FISH, FGFR1, 8p11-12
  • FISH, PDGFRB, 5q33.1
  • Hyperdiploidy with Trisomy 4, 10, and 17
  • IGH Rearrangement
  • IGH-BCL2 Fusion
  • IGH-CCND1 Fusion
  • IGH-FGFR3 Fusion
  • IGH-MAF Fusion
  • Inv(16)
  • Inv(16)(p13.3q22)
  • KMT2A (MLL) Rearrangement
  • oncology FISH
  • p16 (CDKN2) Deletion
  • p53 (TP53) Deletion
  • PDGFR-alpha Rearrangement
  • PDGFR-beta Rearrangement
  • PDGFRa Rearrangement
  • PDGFRA-CHIC2-FIP1L1
  • PDGFRb Rearrangement
  • Philadelphia chromosome
  • PML-RARa Fusion
  • RUNX1T1-RUNX1 (ETO-AML1) Fusion
  • SYT (SS18) Rearrangement
  • t(11;14)(q13;q32)
  • t(12;21)(p13;q22)
  • t(14;16)(q32;q23.1)
  • t(14;18)(q32;q21)
  • t(15;17)(q24;q21)
  • t(4;14)(p16;q32)
  • t(8;21)(q22;q22)
  • t(9;22)(q34;q11.2)
  • TCF3 (E2A) Rearrangement
  • Trisomy 12
  • Trisomy 8