Chromosome FISH, CLL Panel
2002295
Ordering Recommendation
Alternate test to detect prognostically important genomic abnormalities in CLL.
Mnemonic
FISH CLLP
Methodology
Fluorescence in situ Hybridization
Performed
Sun-Sat
Reported
3-10 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
- Patient Preparation
- Collect
- Green (sodium heparin). Also acceptable: Non-diluted bone marrow aspirate collected in a heparinized syringe.
- Specimen Preparation
- Transport 5 mL whole blood (Min: 2 mL). OR Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL)
- Storage/Transport Temperature
- Room temperature.
- Unacceptable Conditions
- Frozen specimens. Paraffin-embedded specimens. Clotted specimens.
- Remarks
- Stability
- Ambient: 48 hours; Refrigerated: 48 hours; Frozen; Unacceptable.
Reference Interval
By report
Interpretive Data
See Compliance Statement A: www.aruplab.com/CS
Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.
Note
Fluorescence in situ Hybridization panel is performed for CLL prognosis-specific genomic abnormalities as follows: ATM deletion, D13S319 deletion, Trisomy 12, TP53 deletion.
A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
CPT Code(s)
88271 x4; 88275 x4; 88291
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0092616 | Chromosome FISH, CLL Panel | 57802-1 |
| 2002197 | EER Chromosome FISH, CLL Panel | 11526-1 |
Aliases
- 'Chronic Lymphocytic Leukemia FISH Panel