HNPCC/Lynch Syndrome Deletion/Duplication
2001728
 
Ordering Recommendation
This is a second tier test and REQUIRES PERMISSION fromARUPs Genetic Counselor (800-242-2787, x2141) before ordering.
Mnemonic
HNPCC DD
Methodology
Polymerase Chain Reaction/Multiplex Ligation-dependent Probe Amplification
Performed
Varies
Reported
Within 14 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory.
Specimen Required
Patient Preparation
 
Collect
Contact ARUP's genetic counselor at (800) 242-2787 extension 2141 prior to test submission for collection requirements.  
Specimen Preparation
 
Storage/Transport Temperature
 
Unacceptable Conditions
 
Remarks
 
Stability
 
Reference Interval
Interpretive Data
Refer to report.



Counseling and informed consent are recommended for genetic testing. Consent forms are available online at www.aruplab.com.

See Compliance Statement C: www.aruplab.com/CS
Note
Available for MLH1, MSH2, MSH6 or PMS2 genes. For PMS2 testing, suspected deletions or duplications in exons 12-15 require sequencing to exclude pseudogene copy number variants. Additional charges apply.
CPT Code(s)
For MLH1, 81294; for MSH2, 81297; for MSH6, 81300; for PMS2, 81319; if pseudogene analysis is performed, add: 81479
Components
Component Test Code*Component Chart Name
2001729HNPCC DD Specimen
2001730HNPCC/Lynch Syndrome, MMR Gene
2001731HNPCC Deletion/Duplication Interp
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • HNPCC/Lynch Syndrome (MLH1) (HNPCC/Lynch Syndrome Deletion/Duplication)
  • HNPCC/Lynch Syndrome (MSH2) (HNPCC/Lynch Syndrome Deletion/Duplication)
  • HNPCC/Lynch Syndrome (MSH6) (HNPCC/Lynch Syndrome Deletion/Duplication)
  • HNPCC/Lynch Syndrome (PMS2) (HNPCC/Lynch Syndrome Deletion/Duplication)
  • Lynch Syndrome/HNPCC (HNPCC/Lynch Syndrome Deletion/Duplication)