Use to assess immunocompetence following Neisseria meningitidis vaccination. To assess suspected immunodeficiency, use pre- and postvaccination serology. Do not use for diagnosis of infection or serotyping.
- Patient Preparation
- Collect
- Serum separator tube.
- Specimen Preparation
- Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
- Storage/Transport Temperature
- Refrigerated.
- Unacceptable Conditions
- Remarks
- Stability
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
0.9 µg/mL or less: Antibody concentration not protective.
1.0-2.0 µg/mL: Equivocal.
2.1 µg/mL or greater: Antibody to Neisseria meningitidis detected. Suggestive of protection.
Responder status is determined according to the ratio of the one month post-vaccination concentration to pre-vaccination concentration of IgG antibodies to N. meningitidis (Types A, C, Y, and W-135) as follows:
1. If the one month post-vaccination concentration is less than 3.0 µg/mL, the patient is considered to be a non-responder.
2. If the one month post-vaccination concentration is greater than or equal to 3.0 µg/mL, a patient with a ratio of greater than or equal to 4 is a good responder, a ratio of 2-4 is a weak responder, and a ratio of less than 2 is considered a non-responder
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2001604 | N.meningitidis Type A IgG | 28546-0 |
2001605 | N.meningitidis Type C IgG | 28547-8 |
2001606 | N.meningitidis Type Y IgG | 60466-0 |
2001607 | N.meningitidis Type W-135 IgG | 60465-2 |
- Meningococcal IgG Vaccine Response
- N. Meningitidis IgG Vaccine Response
- Neisseria meningitidis
- Vaccine Response