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Antimicrobial Susceptibility - Carbapenemase Production
2001503
Ordering Recommendation

Determine production of carbapenem-inactivating enzymes in gram negative bacterial organisms.

Mnemonic
MA KPC
Methodology
Disk Diffusion / Chromogenic Assay
Performed
Sun-Sat
Reported
2-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Actively growing Enterobacteriaceae species or Pseudomonas aeruginosa in pure culture. 
Specimen Preparation
Transport sealed container with pure culture on agar slant or in bacterial transport media.  Place each specimen in an individually sealed bag. 
Storage/Transport Temperature
Room temperature. 
Unacceptable Conditions
Mixed cultures or non-viable organisms. 
Remarks
Isolate identification and specimen source required. 
Stability
Ambient: 1 week; Refrigerated: 48 hours; Frozen: Unacceptable 
Reference Interval
Negative
Interpretive Data
Carbapenemase production is a common mechanism of carbapenem resistance. For guidance on treatment of carbapenemase producers, consultation with an Infectious Disease physician is recommended.

Note
An additional processing fee will be billed for all organisms not submitted in pure culture, as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.
CPT Code(s)
CPT codes vary based on method
Components
Component Test Code*Component Chart NameLOINC
2001503Susceptibility, Carbapenemase
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Carbapenem resistance
  • carbapenem-resistance
  • carbapenems
  • Enterobacteriaceae
  • Hodge Test
  • KPC
  • MDR
  • multi-drug resistance
  • NDM
  • New-Delhi methallo-B-lactamase