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Cytology, ThinPrep Pap Test with Reflex to Human Papillomavirus (HPV), High Risk, E6/E7 mRNA by Transcription-Mediated Amplification (TMA)
2000138
Ordering Recommendation

FDA-approved test for routine 3-year interval cervical cancer screening test in all women ≥21 years. Optional to use for cervical cancer screening at 3-year intervals in women 25-65 years; preferred cotesting panel is Cytology, ThinPrep Pap Test and Human Papillomavirus (HPV), High Risk by Transcription-Mediated Amplification (TMA) (for routine co-testing in women over 30) (2000136).

Mnemonic
TR REQUEST
Methodology
Microscopy/Qualitative Transcription-mediated Amplification
Performed
Sun-Sat
Reported
1-7 days, if reflexed, add 2 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Cervical specimen in a ThinPrep Pap Test collection kit, broom kit (ARUP Supply #12587) or brush/spatula kit (ARUP Supply #40624) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. 
Specimen Preparation
Transport cervical specimen in the original collection kit. 
Storage/Transport Temperature
Room temperature. 
Unacceptable Conditions
Specimens not collected in a ThinPrep Pap Test collection kit or specimens submitted in an expired collection kit. 
Remarks
 
Stability
Ambient: 3 weeks; Refrigerated: 3 weeks; Frozen: Unacceptable 
Reference Interval
Interpretive Data
Refer to report.

Note
If the ThinPrep Pap Test is interpreted as atypical squamous cells of undetermined significance (ASC-US), then Human Papillomavirus (HPV), High Risk, E6/E7 mRNA by Transcription-Mediated Amplification (TMA) will be added. Additional charges apply.

The Pap test is a screening test for cervical cancer and its precursors with an inherent false-negative rate.

The ThinPrep 2000 System is for use in screening for the presence of atypical cells, cervical cancer, or precursor lesions (LSIL, HSIL) as well as other cytologic categories as defined by the Bethesda System for Reporting Cervical Cytology, and is intended as a replacement for the conventional method of Pap smears.

Store PreservCyt Solution without cytologic samples at 15°C to 30°C in the vials provided. Do not use solution beyond expiration date marked on the vial.
Hotline History
View Hotline History
CPT Code(s)
88142; if reviewed by pathologist add 88141. If reflexed add 87624
Components
Component Test Code*Component Chart NameLOINC
2000554ThinPrep Pap Specimen Source
2000555Clinical History
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cytology
  • Pap
  • Pap Smear
  • Pap Test
  • Thin Prep Pap with reflex to HPV HR E6/E7
  • Thin Prep reflex HPV
  • ThinPrep
  • ThinPrep Pap
  • ThinPrep Pap Test with reflex to HR HPV
  • ThinPrep Reflex to HPV