Prostate Specific Antigen, Ultrasensitive
0098581
Ordering Recommendation
Do not use for initial prostate cancer screening; preferred test is total prostate specific antigen (0070121) in conjunction with digital rectal exam. May be used to monitor disease after radical prostatectomy.
Mnemonic
PSA ULTRA
Methodology
Quantitative Electrochemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube or plasma separator tube. Also acceptable: Plain red, green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).  
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Grossly hemolyzed specimens. Vaginal washings.  
Remarks
  
Stability
After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 6 months  
Reference Interval
0.00-4.00 ng/mL  
Interpretive Data
After radical prostatectomy, the reference interval is less than 0.05 ng/mL if there is no residual disease. In healthy males without prostatectomy, the reference interval is 4.00 ng/mL or less. Lower limit of detection is 0.01 ng/mL.

The Roche PSA electrochemiluminescent immunoassay is used. Results obtained with different test methods or kits cannot be used interchangeably. The Roche PSA method is approved for use as an aid in the detection of prostate cancer when used in conjunction with a digital rectal exam in men age 50 and older. The Roche PSA is also indicated for the serial measurement of PSA to aid in the prognosis and management of prostate cancer patients. Elevated PSA concentrations can only suggest the presence of prostate cancer until biopsy is performed. PSA concentrations can also be elevated in benign prostatic hyperplasia or inflammatory conditions of the prostate. PSA is generally not elevated in healthy men or men with nonprostatic carcinoma.  
Note
 
CPT Code(s)
84153
Components
Component Test Code*Component Chart Name
0098581PSA, Ultrasensitive
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Post Prostatectomy
  • PSA, Third Generation
  • Ultrasensitve PSA