Lymphocyte Antigen Proliferation
0096055
Time SensitiveTime Sensitive

Ordering Recommendation
Submit With Order
Mnemonic
LAPP
Methodology
Cell Culture
Performed
Tue-Fri
Reported
9-10 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect control specimen from a healthy individual unrelated to patient at approximately the same time as and under similar conditions to the patient.  
Collect
Green (sodium heparin) (patient) AND green (sodium heparin) (control). Also acceptable: Yellow (ACD Solution A) (patient) AND yellow (ACD Solution A) (control). Patient and control specimens must be collected within 48 hours of test performance.  
Specimen Preparation
Transport 10 mL whole blood (patient) AND 10 mL whole blood (control) in original collection tubes. (Min: 7 mL (patient) AND 7 mL (control)) Do not refrigerate or freeze. LIVE LYMPHOCYTES REQUIRED.
Infant Minimum: 3 mL (patient) AND 7 mL (control).  
Storage/Transport Temperature
CRITICAL ROOM TEMPERATURE.  
Unacceptable Conditions
Yellow (ACD Solution B). Refrigerated or frozen specimens. Specimens in transport longer than 48 hours.  
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
Candida and tetanus antigens are tested independently in lymphocyte culture. Lymphocyte proliferation in response to these antigens is determined by 3H-thymidine incorporation.

Results are reported as the counts per minute (CPM) antigen stimulated versus control cultures and a stimulation index (SI) which represents the ratio of mean CPM of the stimulated lymphocytes to the mean CPM of the unstimulated control.

See Compliance Statement B: www.aruplab.com/CS
Note
Interpretation comparing the patient results to the client normal control and the laboratory control will be provided by the medical director.
CPT Code(s)
86353 x2
Components
Component Test Code*Component Chart Name
0096055Lymphocyte Ag Proliferation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Antigen Proliferation, Lymphocytes