May assist in the diagnosis of ankylosing spondylitis, juvenile rheumatoid arthritis, and Reiter's syndrome. This test is not diagnostic for these disorders and should be correlated with other clinical signs and symptoms. Flow cytometry is the preferred test for most patients since its sensitivity and specificity are nearly equivalent to Ankylosing Spondylitis (HLA-B27) Genotyping (0050392).
- Patient Preparation
- Lavender Hemogard (EDTA), pink Hemogard (K2EDTA), or green Hemogard (sodium or lithium heparin). Hemogard tubes are preferred for laboratory safety.
- Specimen Preparation
- Transport 4 mL whole blood. (Min: 0.5 mL)
- Storage/Transport Temperature
- CRITICAL ROOM TEMPERATURE.
- Unacceptable Conditions
- Frozen or refrigerated specimens. Specimens older than 72 hours. Clotted or hemolyzed specimens.
New York State Clients: Frozen or refrigerated specimens. Heparin specimens older than 48 hours or EDTA specimens older than 30 hours. Clotted or hemolyzed specimens.
- Specimens must be analyzed within 72 hours of collection.
New York State Clients: EDTA specimens must be analyzed within 30 hours of collection. Heparin specimens must be analyzed within 48 hours of collection.
- Ambient: 72 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
New York State Clients: Ambient: 30 hours in EDTA, 48 hours in heparin; Refrigerated: Unacceptable; Frozen: Unacceptable
The performance characteristics of this test were determined by ARUP Laboratories, Inc.
|Component Test Code*||Component Chart Name||LOINC|
- Ankylosing Spondylitis
- HLA Antigen B27
- HLA-B27 Antigen