Ordering Recommendation

Calculate glomerular filtration rate in patients for whom serum creatinine may be misleading, such as the very obese, elderly, or malnourished patients.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST), Plasma Separator Tube (PST), or Green (Lithium or Sodium Heparin).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Grossly hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 3 months

Methodology

Quantitative Nephelometry

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
Components
Reference Interval
  Cystatin C 0.5 - 1.2 mg/L

Interpretive Data

eGFR by Cystatin C Calculation not reported for Age 17 years or less


eGFR Range (mL/min/BSA)
Interpretive Data
90 or greater Stage 1: Normal or increased eGFR
60-89 Stage 2: Mildly decreased eGFR
30-59 Stage 3: Moderately descreased eGFR
15-29 Stage 4: Severely decreased eGFR
Less than 15 Stage 5: Kidney Failure

Compliance Category

FDA

Note

If the patient's age and/or gender is unknown or is 18 years or younger, then Cystatin C Reflex will not be ordered.  If age is greater than 18, Cystatin C reflex will be added at no additional charge.

Hotline History

N/A

CPT Codes

82610

Components

Component Test Code* Component Chart Name LOINC
0095228 Cystatin C 33863-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Cystatin C, Serum with Reflex to Estimated Glomerular Filtration Rate (eGFR)