Bile Acids, Fractionated and Total by LC-MS/MS
Ordering Recommendation

Do not use to diagnose liver dysfunction. Use to screen for inborn errors of bile acid metabolism or monitor bile acid therapy.

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Tue, Thu, Sat
1-6 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Patient should fast for a minimum of eight hours prior to specimen collection. 
Plain red or serum separator tube. 
Specimen Preparation
After clot formation, centrifuge specimen and pour off serum into a transport tube. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) 
Storage/Transport Temperature
Refrigerated. Store specimen refrigerated or frozen. 
Unacceptable Conditions
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 3 months 
Reference Interval
7 years and older:
Cholic acid (CA) 0-1.9 µmol/L
Chenodeoxycholic acid (CDC) 0-3.4 µmol/L
Deoxycholic acid (DCA) 0-2.5 µmol/L
Ursodeoxycholic acid (UDC) 0-1.0 µmol/L
Total 0-7.0 µmol/L
Interpretive Data

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Reference intervals were derived using samples obtained after an overnight fast.
Hotline History
Component Test Code*Component Chart NameLOINC
0092611Bile Acids - Cholic Acid30518-5
0092612Bile Acids - Deoxycholic Acid30520-1
0092613Bile Acids - Chenodeoxycholic Acid30519-3
0092614Total Bile Acids14628-2
0093240Bile Acids - Ursodeoxycholic Acid55159-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Bile Salts
  • Chenodeoxycholic Acid
  • Cholic Acid
  • Deoxycholic Acid
  • Fractionated Bile Acids
  • Ursodeoxycholic Acid (UDC)