17-Hydroxyprogesterone Quantitative by HPLC-MS/MS, Serum or Plasma
Ordering Recommendation
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum Separator Tube (SST). Also acceptable: Plain Red, Pink (K2EDTA), Plasma Separator Tube (PST), Green (Sodium Heparin), or Green (Lithium Heparin). 
Specimen Preparation
Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Frozen. Also acceptable: Refrigerated. 
Unacceptable Conditions
Grossly hemolyzed specimens. 
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months 
Reference Interval
Effective August 19, 2013
Premature (26-28 weeks)124-841 ng/dL124-841 ng/dL
Premature (29-35 weeks)26-568 ng/dL26-568 ng/dL
Full term Day 37-77 ng/dL7-77 ng/dL
4 days-30 days7-106 ng/dLLess than 200 ng/dL
1 month-2 months13-106 ng/dLLess than 200 ng/dL
3 months-5 months13-106 ng/dL3-90 ng/dL
6  months-1 yearLess than or equal to 148 ng/dLLess than or equal to 148 ng/dL
2-3 yearsLess than or equal to 256 ng/dLLess than or equal to 228 ng/dL
4-6 yearsLess than or equal to 299 ng/dLLess than or equal to 208 ng/dL
7-9 yearsLess than or equal to 71 ng/dLLess than or equal to 63 ng/dL
10-12 yearsLess than or equal to 129 ng/dLLess than or equal to 79 ng/dL
13-15 years9-208 ng/dL9-140 ng/dL
16-17 yearsLess than or equal to 178 ng/dL24-192 ng/dL
18 years and olderLess than 207 ng/dLLess than 139 ng/dL
Follicular15-70 ng/dLDoes Not Apply
Luteal35-290 ng/dLDoes Not Apply
Tanner Stage ILess than or equal to 74 ng/dLLess than or equal to 62 ng/dL
Tanner Stage IILess than or equal to 164 ng/dLLess than or equal to 104 ng/dL
Tanner Stage III13-209 ng/dLLess than or equal to 151 ng/dL
Tanner Stage IV-V7-170 ng/dL20-173 ng/dL

Interpretive Data

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
Component Test Code*Component Chart NameLOINC
009233217-Hydroxyprogesterone, HPLC-MS/MS1668-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • 17-OHP
  • 17a
  • 17a-OH
  • Hydroxyprogesterone
  • Progesterone