Feedback
Chlorpromazine
0090870
Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
CHLORP
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Wed, Sat
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. 
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA). 
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Whole blood. Light blue (citrate) or yellow (SPS or ACD solution). 
Remarks
 
Stability
After separation from cells: Ambient: 12 hours; Refrigerated: 72 hours; Frozen: 5 days 
Reference Interval
Effective February 19, 2013
Child (0 - 11 years)
Adult (12 years and older)
Therapeutic Range30-80 ng/mL50-300 ng/mL
Toxic LevelGreater than 200 ng/mLGreater than 750 ng/mL

Interpretive Data
Toxic concentrations may cause drowsiness, coma, hypotension, tachycardia and seizures. Large daily doses of chlorpromazine may cause phenothiazine sudden death syndrome.

Note
Hotline History
View Hotline History
CPT Code(s)
Components
Component Test Code*Component Chart NameLOINC
0090870Chlorpromazine3471-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Largactil
  • Ormazine
  • Thorazine
  • Thorazine Spansule