Chlorpromazine (Temporary Referral as of 07/09/19)
Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Wed, Sat
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. 
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA). 
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Whole blood. Light blue (citrate) or yellow (SPS or ACD solution). 
After separation from cells: Ambient: 12 hours; Refrigerated: 72 hours; Frozen: 5 days 
Reference Interval
Effective February 19, 2013
Child (0 - 11 years)
Adult (12 years and older)
Therapeutic Range30-80 ng/mL50-300 ng/mL
Toxic LevelGreater than 200 ng/mLGreater than 750 ng/mL

Interpretive Data
Toxic concentrations may cause drowsiness, coma, hypotension, tachycardia and seizures. Large daily doses of chlorpromazine may cause phenothiazine sudden death syndrome.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
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CPT Code(s)
Component Test Code*Component Chart NameLOINC
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Largactil
  • Ormazine
  • Thorazine
  • Thorazine Spansule