Lorazepam
0090181
Ordering Recommendation
Optimize drug therapy and monitor patient adherence.
Mnemonic
LORAZ
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Tue, Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
- Patient Preparation
- Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
- Collect
- Gray (Potassium Oxalate/Sodium Fluoride). Also acceptable: Plain Red, Green (Sodium Heparin), Lavender (K2 or K3EDTA) or pink (K2EDTA).
- Specimen Preparation
- Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
- Storage/Transport Temperature
- Refrigerated.
- Unacceptable Conditions
- Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.
- Remarks
- Stability
- After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles)
Reference Interval
Effective November 18, 2013
Dose-Related Range: | 50-240 ng/mL - Dose (Adult): 1-10 mg/d |
Toxic: | Greater than 300 ng/mL |
Interpretive Data
Adverse effects may include respiratory depression, sedation, dizziness, weakness and lethargy.
Note
Hotline History
N/A
CPT Code(s)
80346 (Alt code: G0480)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0090181 | Lorazepam | 3724-2 |
Aliases
- Ativan
- ativan blood level