Mucopolysaccharides Screen - Electrophoresis & Quantitation, Urine
0081352
 
Ordering Recommendation
Use to evaluate symptomatic patients for mucopolysaccharidoses (MPS). To monitor glycosaminoglycans (GAGs) in patients previously diagnosed with MPS, refer to Mucopolysaccharides, Quantitative, Urine (0081357).
Mnemonic
MPS SCREEN
Methodology
Electrophoresis/Spectrophotometry
Performed
Tue
Reported
4-14 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Morning void preferred.  
Collect
Urine.  
Specimen Preparation
Freeze specimen immediately. Transport 20 mL urine. (Min: 10 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Specimens containing preservatives.  
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
Mucopolysaccharides, Electrophoresis Pattern By report
0081357Mucopolysaccharides, Quantitative, Urine 0-​5 months: 14.6-​47.8 mg/mmol creatinine
6-​11 months: 3.7-​35.5 mg/mmol creatinine
1-​2 years: 5.4-​30.8 mg/mmol creatinine
3-​6 years: 5.2-​16.7 mg/mmol creatinine
7-​13 years: 2.4-​10.2 mg/mmol creatinine
14 years or older: 0.0-​7.1 mg/mmol creatinine
Interpretive Data
Mucopolysaccharides (Glycosaminoglycans) include: Keratan Sulfate, Heparan Sulfate, Dermatan Sulfate, and Chondroitin Sulfates 4 and 6. The excretion of Heparan Sulfate is variable. A normal mucopolysaccharides screen does not exclude Sanfilippo Syndrome (Mucopolysaccharidosis Type III).

See Compliance Statement B: www.aruplab.com/CS
Note
CPT Code(s)
83866; 83864
Components
Component Test Code*Component Chart Name
0081353MPS Electrophoresis
0081355Mucopolysaccharides mg/mmol CRT
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Chondroitin Sulfate
  • Dermatan Sulfate
  • GAG(s)
  • Glycosaminoglycans
  • Heparan Sulfate
  • Urine mucopolysaccharides
  • urine mucopolysaccharides screen