Squamous Cell Carcinoma Antigen, Serum
Ordering Recommendation

Useful as a tumor marker for squamous cell carcinomas of the head and neck, uterine cervix, lung, vulva, and esophagus.

Quantitative Enzyme-Linked Immunosorbent Assay
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube or plain red. 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Specimens exposed to repeated freeze/thaw cycles. 
After separation from cells: Ambient: 48 hours; Refrigerated: 4 months; Frozen: 4 months 
Reference Interval
2.2 ng/mL or less
Interpretive Data
SCC antigen levels alone should not be interpreted as evidence to the presence or absence of malignant disease. In patients with known or expected cancer, other tests and procedures must be considered for diagnosis and patient management. Results obtained with different assay methods or kits cannot be used interchangeably.

Compliance Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.

Component Test Code*Component Chart NameLOINC
0081054Squamous Cell Carcinoma Antigen9679-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • SCC
  • SCC Antigen
  • SCCA