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Maternal Serum Screen, Alpha Fetoprotein (Only)
0080434
Ordering Recommendation

Order this test for PREGNANT FEMALE patients only.  For males or non-pregnant females, refer to Alpha Fetoprotein, Serum (Tumor Marker) (0080428).

Mnemonic
MS ONLY
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
2-3 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. 
Collect
Serum separator tube or plain red. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Plasma. Specimens exposed to repeated freeze/thaw cycles. Hemolyzed specimens. 
Remarks
The following information is required and must accompany the specimen in order for testing to be interpreted: patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient was diabetic at the time of conception, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol), physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. 
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year 
Reference Interval
By report
Interpretive Data


Note
This test is used to screen for fetal risk of Open Neural Tube Defect (i.e., spina bifida).
Components
Component Test Code*Component Chart NameLOINC
0080021Patient's AFP1834-1
0080241Estimated Due Date11778-8
0080917Maternal Weight29463-7
0080918MoM for AFP20450-3
0080920Maternal Screen Interpretation49586-1
0080922Specimen19151-0
0080923Dating21299-3
0080924Insulin Req Maternal Diabetes44877-9
0080925Family Hx Neural Tube Defect8670-2
0080926Maternal Race21484-1
0080927Number of Fetuses11878-6
0080932Maternal Age At Delivery21612-7
0080938Gestational Age (Exact)18185-9
0081158Family History of Aneuploidy32435-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • AFP
  • AFP Maternal Screening
  • AFP Neural Tube Defects
  • Maternal Screening, AFP Single Marker