Serotonin, Whole Blood
0080395
Ordering Recommendation
 
Mnemonic
SEROT-WB
Methodology
Quantitative High Performance Liquid Chromatography
Performed
Sun, Tue-Fri
Reported
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Abstain from medications for 72 hours prior to collection.  
Collect
Lavender (EDTA) or pink (K2EDTA).  
Specimen Preparation
Place on ice. Transfer 3 mL whole blood to an ARUP Serotonin Transport Tube containing ascorbic acid (ARUP supply #16568). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL) Mix well. Specimen must be preserved and frozen within 2 hours of collection.  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Non-frozen specimens. Specimens other than whole blood.  
Remarks
Serotonin, Serum (ARUP test code 0080397) is recommended for patients that are difficult to draw.  
Stability
After transfer to Serotonin Transport Tube: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month  
Reference Interval
50-200 ng/mL  
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS  
Note
Medications that may affect serotonin concentrations include lithium, MAO inhibitors, methyldopa, morphine, and reserpine.  In general, foods that contain serotonin do not interfere significantly.  Slight increases may be seen in acute intestinal obstruction, acute MI, cystic fibrosis, dumping syndromes, and nontropical sprue.  Metastasizing abdominal carcinoid tumors often show serotonin concentrations greater than 400 ng/mL.
CPT Code(s)
84260
Components
Component Test Code*Component Chart Name
0080395Serotonin, Whole Blood
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 5-HT
  • 5-Hydroxy Tryptamine
  • 5-Hydroxytryptamine