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Ehlers-Danlos Syndrome Type VI Screen
0080351
Ordering Recommendation

Initial test to diagnose or rule out Ehlers-Danlos Syndrome, Type VI A (kyphoscoliotic type). This testing is NOT recommended to screen for other types of EDS.

Mnemonic
EDS6
Methodology
High Performance Liquid Chromatography
Performed
Wed
Reported
6-14 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
First-morning urine is preferred. 
Collect
Urine. First-morning void. Also acceptable: Random specimens. 
Specimen Preparation
Transfer 4 mL urine to an ARUP Standard Transport Tube. (Min: 3 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months 
Reference Interval
Age
PYR
DPYR
Ratio DPYR/PYR
0-11 monthsNot applicableNot applicable0.13-0.20
1-3 yearsNot applicableNot applicable0.18-0.24
4-9 yearsNot applicableNot applicable0.19-0.25
10-14 yearsNot applicableNot applicable0.17-0.27
15-19 yearsNot applicableNot applicable0.20-0.26
20 years and olderNot applicableNot applicable0.23-0.29

Interpretive Data


Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
For pyridinoline and deoxypyridinoline quantitative results, order Pyridinoline & Deoxypyridinoline by HPLC (0080342).
Components
Component Test Code*Component Chart NameLOINC
0080352Pyridinoline, pmol/mL
0080353Deoxypyridinoline, pmol/mL
0080354EDS6 Ratio
0080357EDS6 Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EDS VI
  • pyridinoline and deoxypyridnoline