Not a first-line test for suspected catecholamine-secreting neuroendocrine tumors (pheochromocytoma or neuroblastoma).
- Patient Preparation
- Patient should be calm and supine for 30 minutes prior to collection.
- Green (sodium or lithium heparin). Collect on ice.
- Specimen Preparation
- Specimen should be centrifuged and frozen within one hour (refrigerated centrifuge is preferred but not required). Transfer 4 mL plasma to an ARUP Standard Transport
Tube. (Min: 2.1 mL)
- Storage/Transport Temperature
- CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
- Unacceptable Conditions
- EDTA plasma, serum, or urine.
- After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen at -20°C: 1 month; Frozen at -70°C: 1 year
|Test Number||Components||Reference Interval|
| ||Dopamine||2 days and older: 0-20 pg/mL|
probability of a neuroendocrine tumor. Measurement of plasma or urine fractionated metanephrines provides better diagnostic sensitivity than measurement of catecholamines.
Higher catecholamine concentrations are observed in specimens collected from upright or standing adults. Epinephrine may be increased by approximately 20 percent; norepinephrine up to 700 pg/mL; dopamine, unchanged.
For optimum results, patient should be supine for 30 minutes prior to collection.
Children, particularly those under 2 years of age, often show an elevated catecholamine response to stress.
|Component Test Code*||Component Chart Name||LOINC|
- Catecholamine Fractionation
- Catecholamines, Free
- Plasma Catecholamines