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Hemoglobin A1c
Ordering Recommendation

Use to diagnose and monitor diabetes mellitus. Monitor prediabetes.

Quantitative High Performance Liquid Chromatography/Boronate Affinity
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Lavender (EDTA) or pink (K2EDTA). 
Specimen Preparation
Transport 5 mL whole blood in original tube. (Min: 1 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Tissue or urine. 
Ambient: 24 hours; Refrigerated: 1 month; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Effective May 21, 2012
Available SeparatelyComponentsReference Interval
NoHemoglobin A1c4.0-5.6%
NoEstimated Average GlucoseBy report

Interpretive Data
Hemoglobin A1c values of 5.7-6.4 percent indicate an increased risk for developing diabetes mellitus. Hemoglobin A1c values greater than or equal to 6.5 percent are diagnostic of diabetes mellitus. Diagnosis should be confirmed by repeating the Hb A1c test.

This boronate affinity Hb A1c method provides accurate analytical results in the presence of nearly all hemoglobin variants. Hb F higher than 10 percent of total Hb may yield falsely low results. Conditions that shorten red cell survival, such as the presence of unstable hemoglobins like Hb SS, Hb CC, and Hb SC, or other causes of hemolytic anemia may yield falsely low results. Iron deficiency anemia may yield falsely high results.

Component Test Code*Component Chart NameLOINC
0070427Estimated Average Glucose27353-2
0070428Hemoglobin A1C4548-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • A1C
  • A1c Hemoglobin
  • Glycated Hemoglobin
  • Glyco HGB
  • Glyco-Hb
  • Glycosylated Hemoglobin
  • HA1C
  • HbA1c
  • Hemoglobin A1C
  • Hemoglobin A1c, Blood
  • HgbA1c