Preferred test to measure bone resorption and monitor response to antiresorptive therapy (eg, bisphosphonates, hormone replacement therapy) in postmenopausal women and individuals with osteoporosis.
- Patient Preparation
- For patients receiving therapy with high biotin doses (e.g. greater than 5 mg/day), specimen should not be drawn until at least 8 hours after the last biotin administration.
- Collect
- Serum separator tube, pink (K2EDTA), or green (lithium heparin).
- Specimen Preparation
- Allow serum separator tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
- Storage/Transport Temperature
- Frozen.
- Unacceptable Conditions
- Hemolyzed specimens.
- Remarks
- Stability
- After separation from cells: Ambient: 4 hours; Refrigerated: 8 hours; Frozen: 3 months
Age | Female | Male |
---|---|---|
6 months-6 years | 500-1800 pg/mL | 500-1700 pg/mL |
7-9 years | 566-1690 pg/mL | 522-1682 pg/mL |
10-12 years | 503-2077 pg/mL | 553-2071 pg/mL |
13-15 years | 160-1590 pg/mL | 485-2468 pg/mL |
16-17 years | 167-933 pg/mL | 276-1546 pg/mL |
18-29 years | 64-640 pg/mL | 87-1200 pg/mL |
30-39 years | 60-650 pg/mL | 70-780 pg/mL |
40-49 years | 40-465 pg/mL | 60-700 pg/mL |
50-69 years | 40-840 pg/mL | |
70 years or greater | 52-847 pg/mL | |
Postmenopausal | 104-1008 pg/mL |
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0070415 | C-Telopeptide, Beta-Cross-Linked, Serum | 41171-0 |
- Beta-CTx
- ?-Cross Laps
- B-CTx
- Beta-Cross Laps
- bone resorption marker
- C-Telopeptide
- C-terminal collagen crosslinks
- Carboxy terminal collagen crosslinks
- Collagen C Telopeptide
- Collagen Type I-C
- Collagen Type I-C Telopeptide
- CTx