IGF-1 (Insulin-Like Growth Factor 1)
0070125
Ordering Recommendation
Aids in diagnosis of growth hormone excess or deficiency disorders.
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Mnemonic
IGF-1
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Transport 1 mL serum. (Min: 0.5 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Plasma, tissue, or urine. Grossly hemolyzed or lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year  
Reference Interval
Age Female Male
1-​2 years
3 years
4 years
5 years
6 years
7 years
8-​18 years
19-​20 years
21-​30 years
31-​40 years
41-​50 years
51-​60 years
61-​70 years
71-​80 years
56-​144 ng/mL
26-​162 ng/mL
32-​179 ng/mL
39-​198 ng/mL
55-​238 ng/mL
55-​268 ng/mL
Refer to Tanner Stages
217-​475 ng/mL
87-​368 ng/mL
106-​368 ng/mL
118-​298 ng/mL
53-​287 ng/mL
75-​263 ng/mL
54-​205 ng/mL
30-​122 ng/mL
20-​141 ng/mL
25-​157 ng/mL
30-​174 ng/mL
37-​192 ng/mL
44-​211 ng/mL
Refer to Tanner Stages
281-​510 ng/mL
155-​432 ng/mL
132-​333 ng/mL
121-​237 ng/mL
68-​245 ng/mL
60-​220 ng/mL
36-​215 ng/mL

Female Tanner Stages
I (8-​12 yrs) 64-​358 ng/mL
II (8-​14 yrs) 89-​566 ng/mL
III (9-​15 yrs) 192-​568 ng/mL
IV & V (11-​18 yrs) 147-​646 ng/mL
Male Tanner Stages
I (8-​15 yrs) 52-​391 ng/mL
II & III (8-​16 yrs) 39-​648 ng/mL
IV & V (11-​18 yrs) 144-​673 ng/mL
Interpretive Data
IGF-1 values well above the age and gender matched reference interval indicate a possible pituitary tumor secreting growth hormone. IGF-1 values below the reference interval indicate a possible GH deficiency.
Note
CPT Code(s)
84305
Components
Component Test Code*Component Chart Name
0070125IGF-1 (Insulin-Like Growth I)
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Cross References
  • IGF
  • IGF-1
  • IGF1
  • Insulin-Like Growth Factor 1, Serum
  • Insulin-Like Growth Factor I
  • Somatomedin C