Histamine, Urine
0070038
Ordering Recommendation
Aid in evaluation of patient with allergic signs and symptoms, such as anaphylaxis. May assist when diagnosing and monitoring mast-cell activation disorders or when evaluating histamine production over a longer time frame.
Mnemonic
HIST-U
Methodology
Quantitative Enzyme Immunoassay
Performed
Tue, Sat
Reported
1-6 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
- Patient Preparation
- Collect
- Random or 24-hour urine in a plastic container. Refrigerate during collection.
- Specimen Preparation
- Transfer a 4 mL aliquot from a well-mixed random or 24-hour collection to an ARUP Standard Transport Tube and freeze immediately. (Min: 1 mL) Record total volume and collection time interval on transport tube and test request form.
- Storage/Transport Temperature
- CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
- Unacceptable Conditions
- Room temperature specimens.
- Remarks
- Stability
- Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 6 months
Reference Interval
Effective February 21, 2012
| Components | Reference Interval |
|---|---|
| Histamine, Urine - ratio to CRT | 0-450 nmol/g crt |
| Histamine, Urine, Excretion - 24h | 0-60 µg/day |
Interpretive Data
Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Note
If 24-hour urine is submitted, the excretion will be calculated. If random urine is submitted, the result will be reported as Not applicable.
CPT Code(s)
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020207 | Creatinine, Urine - per volume | 2161-8 |
| 0070039 | Histamine, Urine - per volume | 33290-8 |
| 0070041 | Histamine, Urine - ratio to CRT | 25925-9 |
| 0097110 | Total Volume | 19153-6 |
| 0097111 | Hours Collected | 30211-7 |
| 2005776 | Histamine, Urine, Excretion - 24 h | 9410-2 |
Aliases
- urine histamine