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Calcitonin
0070006
Ordering Recommendation

Diagnose and monitor medullary thyroid carcinoma (MTC). Secondary test to assist in diagnosing multiple endocrine neoplasia type II and familial MTC.

Mnemonic
CALCI
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube or green (sodium or lithium heparin). 
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Tissue or urine. EDTA plasma. Grossly hemolyzed or lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 3 months 
Reference Interval
Male 3 years and older: 0.0-7.5 pg/mL
Female 3 years and older: 0.0-5.1 pg/mL
Interpretive Data
Calcitonin levels greater than 100 pg/mL may occur in the following conditions: medullary thyroid carcinomas (MTC), leukemias, and myeloproliferative disorders.

Provocative testing (calcium) is suggested in patients with MTC if the calcitonin is not clearly diagnostic.

The Siemens Immulite® 2000 method is used. Results obtained with different assay methods or kits cannot be used interchangeably. Calcitonin is useful in monitoring medullary thyroid carcinoma. The calcitonin assay value, regardless of level, should not be interpreted as absolute evidence of the presence or absence of malignant disease.

Note
CPT Code(s)
82308
Components
Component Test Code*Component Chart NameLOINC
0070006Calcitonin1992-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Human Calcitonin
  • Thyrocalcitonin