Parvovirus B 19 Antibody, IgM
Ordering Recommendation
Not recommended as a standalone test. Parvovirus B19 Antibodies, IgG and IgM (0065120) is preferred.
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Refrigerated.
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Mark specimens plainly as "acute" or "convalescent."
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-3 days
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Parvovirus B19 Antibody IgM | 0.90 IV or less |
Interpretive Data
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
Appearance of an IgM antibody response normally occurs 7 to 14 days after the onset of disease. Testing immediately post-exposure is of no value without a later convalescent specimen. A residual IgM response may be distinguished from early IgM response to infection by testing sera from patients three to four weeks later for changing levels of specific IgM antibodies.
Component |
Intrepretation |
---|---|
Parovirus B19 Antibody, IgM | 0.90 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody. 0.91-1.09 IV: Equivocal - Repeat testing in 7-21 days may be helpful. 1.10 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
FDA
Note
Hotline History
CPT Codes
86747
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0065122 | Parvovirus B19 Antibody IgM | 5274-6 |
Aliases
- B19
- B19 IgM Antibodies
- Erythrovirus B19 IgM
- Human Parvovirus B19 IgM