IGH-BCL2 (BCL-2/JH) Translocation, t(14;18) by PCR
0055616
Ordering Recommendation
Diagnosis of follicular lymphoma (FL) in conjunction with clinical, morphologic, and flow cytometric data.
Mnemonic
BCL2C-F
Methodology
Polymerase Chain Reaction
Performed
DNA isolation: Sun-Sat; Assay: Sun-Sat
Reported
2-7 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) OR bone marrow (EDTA) OR tissue.  
Specimen Preparation
Whole blood: Transport 5 mL. (Min: 1 mL) OR Bone marrow: Transport 3 mL. (Min: 1 mL) OR Fresh tissue: Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue. OR FFPE tumor tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing.  Transport block(s) and/or shavings in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Whole blood OR Bone marrow: Refrigerated. Fresh tissue: Frozen on dry ice. FFPE tumor tissue: Room temperature or refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Whole blood OR Bone marrow: Frozen specimens. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.  
Remarks
  
Stability
Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue:
Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue:
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
By report

See Compliance Statement B: www.aruplab.com/CS  
Note
 
CPT Code(s)
81402
Components
Component Test Code*Component Chart Name
0055617IGH-BCL2 (BCL-2/JH) t(14;18) PCR, MBR
0055618IGH-BCL2 (BCL-2/JH) t(14;18) PCR, MCR
2006958IGH_BCL2, Source
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Aliases
  • BCL-2/JH translocation
  • IGH-BCL2 translocation