Allergens, Inhalants, Comprehensive Profile IgE
Ordering Recommendation
Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Multiple patient encounters should be avoided.  
Serum separator tube. Multiple specimen tubes should be avoided.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 3.85 mL serum to an ARUP Standard Transport Tube. (Min: 1.68 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Hemolyzed, icteric, or lipemic specimens.  
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Effective November 17, 2014
Reporting Range
(reported in kU/L)
Probability of IgE Mediated
Clinical Reaction
Class Scoring
Less than 0.10No significant level detected0
0.10 - 0.34Clinical relevance undetermined0/1
0.35 - 0.70Low1
0.71 - 3.50Moderate2
3.51 - 17.50High3
17.51 - 50.00Very high4
50.01 - 100.00Very high5
Greater than 100.00Very high6

Test Number
Reference Interval
0050345Immunoglobulin EEffective November 17, 2014
Reference Interval
0-5 months13 kU/L or less
6-12 months34 kU/L or less
1-2 years97 kU/L or less
3 years199 kU/L or less
4-6 years307 kU/L or less
7-8 years403 kU/L or less
9-12 years696 kU/L or less
13-15 years629 kU/L or less
16-17 years537 kU/L or less
18 years and older214 kU/L or less

Interpretive Data
Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivoreactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.

Allergens included: Alternaria alternata (tenuis), Aspergillus fumigatus, Bermuda Grass, Cat Epithelium & Dander, Common/Short Ragweed, Cottonwood Tree, Cow Hair & Dander, D. farinae (Mites), D. pteronyssinus (Mites), Dog Dander, Elm Tree, English Plantain, Hormodendrum (Cladosporium), Horse Hair & Dander, House Dust Greer, IgE, Serum Total, Johnson Grass, June Grass/Kentucky Bluegrass, Lamb's Quarters, Mesquite Tree, Mountain Cedar (Juniper) Tree, Mugwort, Oak Tree, Olive Tree, Penicillium notatum, Perennial Rye Grass, Russian Thistle, and Timothy Grass.
CPT Code(s)
86003x27; 82785
Component Test Code*Component Chart NameLOINC
0050345Immunoglobulin E19113-0
0055001Allergen, Fungi/Mold, A. alternata IgE6020-2
0055006Allergen, Animal, Cat Dander IgE6833-8
0055007Allergen, Tree, Mountain Cedar Tree IgE6178-8
0055010Allergen, Tree, Cottonwood Tree IgE6090-5
0055017Allergen, Grass, June/Kentucky Blue IgE6153-1
0055021Allergen, Weed, Mugwort IgE6183-8
0055027Allergen, Weed, Russian Thistle IgE6234-9
0055028Allergen, Grass, Perennial Rye IgE7369-2
0055032Allergen, Grass, Timothy Grass IgE6265-3
0055038Allergen, Fungi/Mold, Hormodendrum IgE7415-3
0055041Allergen, Interp, Immunocap Score IgE33536-4
0055042Allergen, Tree, Elm Tree IgE6109-3
0055044Allergen, Animal, Cow Hair/Dander IgE30087-1
0055045Allergen, Tree, Oak Tree IgE6189-5
0055047Allergen, Grass, Johnson Grass IgE6152-3
0055049Allergen, Weed, English Plantain IgE6110-1
0055059Allergen, Animal, Horse Hair/Dander IgE30088-9
0055061Allergen, Fungi/Mold, A. fumigatus IgE6025-1
0055063Allergen, Mites, D. pteronyssinus IgE6096-2
0055064Allergen, Mites, D. farinae IgE6095-4
0055070Allergen, Grass, Bermuda Grass IgE6041-8
0055080Allergen, Fungi/Mold, P. notatum IgE6212-5
0055085Allergen, Weed, Common/Short Ragweed IgE6085-5
0055091Allergen, House Dust Greer IgE9828-5
0055140Allergen, Tree, Mesquite Tree IgE6173-9
0055155Allergen, Tree, Olive Tree IgE6192-9
0055160Allergen, Weed, Lambs Quarters IgE6156-4
0099568Allergen, Animal, Dog Dander IgE6098-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.