Measles (Rubeola) Antibody, IgM, CSF
Ordering Recommendation

Aid in the diagnosis of measles encephalitis. False-positive results will occur due to low incidence of measles in the U.S.

Semi-Quantitative Enzyme-Linked Immunosorbent Assay
1-5 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Specimen Preparation
Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.2 mL) 
Storage/Transport Temperature
Refrigerated. Also acceptable: Frozen. 
Unacceptable Conditions
Specimen types other than CSF. Contaminated, heat-inactivated, or hemolyzed specimens. 
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
0.79 AU or lessNegative - No significant level of IgM antibodies to measles (rubeola) virus detected.
0.80-1.20 AUEquivocal - Repeat testing in 10-14 days may be helpful.
1.21 AU or greaterPositive - IgM antibodies to measles (rubeola) virus detected. Suggestive of current or recent infection or immunization.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

Interpretive Data
The detection of antibodies to rubeola in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0054441Measles, Rubeola, Antibody IgM CSF13283-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • English Measles
  • measles IgM CSF
  • MMR
  • Rubeola IgM CSF