Cytomegalovirus by Quantitative PCR
Ordering Recommendation

Detect and quantify cytomegalovirus (CMV).

Quantitative Polymerase Chain Reaction
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Lavender (EDTA) or pink (K2EDTA), or Bronchoalveolar lavage (BAL). 
Specimen Preparation
Separate plasma from cells. Transfer 1 mL plasma, or whole blood, or BAL to a sterile container. (Min: 0.5 mL). 
Storage/Transport Temperature
Whole blood: Refrigerated. All others: Frozen. 
Unacceptable Conditions
Heparinized specimens. 
Specimen source required. 
Plasma: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year 
Whole blood
: Ambient: 7 days; Refrigerated: 7 days; Frozen: 7 days
Ambient: 24 hours; Refrigerated: 5 days; Frozen: 3 months 
Reference Interval
Not detected
Interpretive Data
The quantitative range of this test is 2.6-6.6 log copies/mL (390-3,900,000 copies/mL) or 2.4-6.4 log IU/mL (227-2,270,000 IU/mL). One IU/mL of CMV DNA is approximately 1.72 copies/mL.

A negative result (less than 2.6 log copies/mL [less than 390 copies/mL] OR less than 2.4 log IU/mL [less than 227 IU/mL]) does not rule out the presence of PCR inhibitors in the patient specimen or CMV DNA concentrations below the level of detection of the test. Inhibition may also lead to underestimation of viral quantitation.

Compliance Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.

The limit of quantification for this DNA test is 2.6 log copies/mL (390 copies/mL) or 2.4 log IU/mL (227 IU/mL). If the test DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)" and "<2.4 log IU/mL (<227 IU/mL)."  If the test DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."
Component Test Code*Component Chart NameLOINC
0051814Cytomegalovirus Quant by PCR, Interp40444-2
0051815Cytomegalovirus Quant by PCR, Log Cpy/mL54206-8
2002316Cytomegalovirus Quant by PCR, Cpy/mL30247-1
2006534Cytomegalovirus Quant by PCR, IU/mL72493-0
2006535Cytomegalovirus Quant by PCR, Log IU/mL72494-8
2012051Cytomegalovirus Quant by PCR, Source31208-2
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