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Celiac Disease Dual Antigen Screen
0051689
Ordering Recommendation

Acceptable single screening test for celiac disease. Screen includes tTG antibodies IgA and IgG, and DGP antibodies IgA and IgG. Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgA (0097709) is the preferred test for screening patients with suspected celiac disease.

Mnemonic
TTG DGP
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon, Wed,  Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
19 Units or less: Negative - No significant level of detectable IgA or IgG antibodies against human tissue transglutaminase or gliadin peptide.

20 Units or greater: Positive - Presence of IgA and/or IgG antibodies against human tissue transglutaminase and/or gliadin peptide; suggests possibility of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis.
Interpretive Data


Note
This test is a combined antibody screen for tissue transglutaminase and deamidated gliadin-derived peptide antibodies, IgA and IgG.
CPT Code(s)
83516
Components
Component Test Code*Component Chart NameLOINC
0051691Celiac Disease Dual Antigen Screen63420-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Celiac Sprue
  • Combined tissue Transglutaminase (tTG) and deamidated (DGP) IgG and IgA
  • combined tTG and DGP IgG and IGA