Celiac Disease Dual Antigen Screen
0051689
Ordering Recommendation
Acceptable single screening test for celiac disease. More expensive than single Tissue Transglutaminase (tTg) Antibody, IgA test (0097709) or Celiac Disease Reflexive Cascade (2008114). Positive results must be confirmed with IgA and IgG tests for tTG and deamidated gliadin peptide (DGP).
Submit With Order
Mnemonic
TTG DGP
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon, Wed, Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
19 Units or less: Negative - No significant level of detectable IgA or IgG antibodies against human tissue transglutaminase or gliadin peptide.

20 Units or greater: Positive - Presence of IgA and/or IgG antibodies against human tissue transglutaminase and/or gliadin peptide; suggests possibility of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis.
Interpretive Data
Note
This test is a combined antibody screen for tissue transglutaminase and deamidated gliadin-derived peptide antibodies, IgA and IgG.
CPT Code(s)
83516
Components
Component Test Code*Component Chart Name
0051691Celiac Disease Dual Antigen Screen
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Celiac Sprue
  • Combined tissue Transglutaminase (tTG) and deamidated (DGP) IgG and IgA
  • combined tTG and DGP IgG and IGA