Ordering Recommendation

Use to determine parental or neonatal RHD copy number(s) and assess the risk of alloimmune hemolytic disease. This test does not identify or distinguish between partial and weak RHD genotypes. For fetal testing, order RhD Gene (RHD) Copy Number, Fetal (3016640) using a fetal specimen.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).

Specimen Preparation

Whole blood: Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Whole blood specimen: Refrigerated.

Unacceptable Conditions

Frozen specimens in glass collection tubes.

Remarks
Stability

Whole blood specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month

Methodology

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring

Performed

Varies

Reported

2-7 days

Reference Interval

By report

Interpretive Data

Refer to report.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Laboratory Developed Test (LDT)

Note

Whole blood is acceptable for paternal specimens.

Hotline History

N/A

CPT Codes

81403

Components

Component Test Code* Component Chart Name LOINC
0050422 RhD Gene (RHD) Copy Number 35465-4
0051369 RhD Gene (RHD) Copy Number Specimen 66746-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • RHD Gene
  • RHD genotyping
RhD Gene (RHD) Copy Number