Feedback
Trypanosoma cruzi Antibody, IgG
0051076
Ordering Recommendation

Aid in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).

Mnemonic
CHAGAS G
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Wed
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days of the acute specimens. Mark specimens plainly as "acute" or "convalescent." 
Storage/Transport Temperature
Refrigerated. Also acceptable: Room temperature or frozen. 
Unacceptable Conditions
Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
Effective November 9, 2017
1.0 IV or lessNegative - No significant level of Trypanosoma cruzi IgG antibody detected.
1.1 IVEquivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.2 IV or greaterPositive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection.

Interpretive Data
This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.

Components
Component Test Code*Component Chart NameLOINC
0051076Trypanosoma cruzi Antibody, IgG59387-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Chagas Antibody, IgG
  • Tcruzi IgG Ab
  • Trypanosoma cruzi Antibody, Total