First-line screening test for ANCA-associated vasculitis. Recommended in the differential evaluation of autoimmune diseases with renal involvement (SLE and anti-glomerular basement membrane disease). Recommended adjunct diagnostic tool to differentiate ulcerative colitis from Crohn disease in IBD.
A reflex panel is available for the workup of suspected vasculitis; refer to ANCA-Associated Vasculitis Profile (ANCA/MPO/PR-3) Reflex to ANCA Titer (2006480).
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma, urine, or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|Component Test Code*||Component Chart Name||LOINC|
|0050811||Anti-Neutrophil Cytoplasmic Ab, IgG||29967-7|
- ANCA IgG
- ANCA IgG Ab