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Extractable Nuclear Antigen Antibodies (SSA 52, SSA 60, and SSB)
0050791
Ordering Recommendation

Differential evaluation of patients with SLE, Sjogren syndrome, polymyositis/dermatomyositis, and/or other tissue diseases or overlapping syndromes.

Mnemonic
SSA/SSB
Methodology
Semi-Quantitative Multiplex Bead Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Plasma or other body fluids.  Contaminated, hemolyzed, or severely lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Effective May 18, 2015
Test Number
Components
Reference Interval
2012074SSA 52 and 60 (Ro) (ENA) Antibodies, IgG
Test NumberComponentsReference Interval
SSA 52 (Ro) (ENA) Antibody, IgG29 AU/mL or Less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
SSA 60 (Ro) (ENA) Antibody, IgG29 AU/mL or Less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive

0050692SSB (La) (ENA) Antibody, IgG
29 AU/mL or lessNegative
30-40 AU/mLEquivocal
41 AU/mL or greaterPositive


Interpretive Data
Refer to report.

Components
Component Test Code*Component Chart NameLOINC
0050691SSA 52 (Ro) (ENA) Antibody, IgG31625-7
0050692SSB (La) (ENA) Antibody, IgG29965-1
2012055SSA 60 (Ro) (ENA) Antibody, IgG53019-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Anti-ENA Anti-Ribonuclear Protein
  • Ro Ab
  • Scl 70 Antibodies
  • Smith (ENA) Antibody, IgG
  • SSA (Ro) (ENA) Antibody, IgG
  • SSA Ro
  • SSB (La) (ENA) Antibody, IgG
  • SSB LA