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Protein Electrophoresis, CSF
0050590
Ordering Recommendation

Evaluate protein composition of cerebrospinal fluid (CSF); not useful for the assessment of multiple sclerosis for which oligoclonal bands in CSF and serum should be utilized (refer to 0081135).

Mnemonic
CSF ELECT
Methodology
Quantitative Electrophoresis
Performed
Mon, Wed, Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
CSF.  
Specimen Preparation
Transport 1 mL CSF. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 month  
Reference Interval
Total Protein: 15-45 mg/dL                      Alpha-2: 0.0-5.4 mg/dL
Pre-albumin: 0.0-3.1 mg/dL                      Beta: 0.0-8.1 mg/dL
Albumin: 8.4-34.2 mg/dL                          Gamma: 0.0-5.4 mg/dL
Alpha-1: 0.0-3.1 mg/dL
Interpretive Data


Note
CSF electrophoresis may be useful in the diagnosis of tumors in the central nervous system or neurological illness. Oligoclonal Band Profile (ARUP test code 0080440) may be more appropriate for patients with suspected multiple sclerosis. Myelin Basic Protein (ARUP test code 0080515) offers little incremental value in the evaluation of multiple sclerosis. For the evaluation of blood brain barrier integrity, Immunoglobulin G, CSF Index (ARUP test code 0050676), included in the Oligoclonal Band Profile test, may be useful.
CPT Code(s)
84157; 84166
Components
Component Test Code*Component Chart NameLOINC
0050015Albumin, CSF2861-3
0050040Alpha-1, CSF2864-7
0050045Alpha-2, CSF2867-0
0050115Beta, CSF2870-4
0050275Gamma, CSF2873-8
0050430Pre-Albumin, CSF2876-1
0050560Total Protein, CSF2880-3
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Aliases
  • Electrophoresis, Protein, Spinal Fluid