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RUNX1-RUNX1T1 (AML1-ETO) Translocation, t(8;21) by RT-PCR (INACTIVE as of 05/19/14: Refer to 2010138)
0050444
Ordering Recommendation
Mnemonic
AML1-ETO
Methodology
Reverse Transcription Polymerase Chain Reaction
Performed
RNA isolation: Sun-Sat; Assay: Varies
Reported
5-10 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or bone marrow (EDTA). 
Specimen Preparation
Transport 5 mL whole blood (Min: 1 mL). OR 3 mL bone marrow (Min: 1 mL).  Specimens must be received within 48 hours of collection due to lability of RNA... 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Serum or plasma. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed specimens. Frozen or clotted specimens. 
Remarks
 
Stability
Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable 
Reference Interval
Interpretive Data
Refer to report.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
CPT Code(s)
81401
Components
Component Test Code*Component Chart NameLOINC
0050444RUNX1-RUNX1T1 (AML1-ETO) t(8;21) RT-PCR21819-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • AML1-ETO
  • AML1-ETO translocation
  • core-binding factor-related AML testing
  • t(8;21)