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Epstein-Barr Virus Antibody to Nuclear Antigen, IgG
0050245
Ordering Recommendation

Order to document past Epstein-Barr virus (EBV) exposure or, in conjunction with other serologic tests, diagnose primary EBV infectious mononucleosis.

Mnemonic
EBV NA
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Mon-Sun
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum Separator Tube (SST). 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Contaminated, heat-inactivated or grossly hemolyzed specimens. 
Remarks
Label specimens plainly as ''acute'' or ''convalescent.'' 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Effective February 19, 2013

17.9 U/mL or less: Not Detected
18.0-21.9 U/mL: Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
Interpretive Data
Interpretive information regarding serologic features of EBV-associated diseases is available at www.arupconsult.com/ebvdx.

Note
EBNA values obtained with different manufacturers' assay methods may not be used interchangeably.  The magnitude of the reported EBNA level cannot be correlated to an endpoint titer.
Hotline History
View Hotline History
Components
Component Test Code*Component Chart NameLOINC
0050245EBV Antibody to Nuclear Antigen IgG30083-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EBNA Antibody
  • EBNA-IgG Ab
  • EBV Antibodies
  • EBV Antibody to Nuclear Antigen
  • EBV Nuclear Antibody