Ordering Recommendation

Aids in evaluation of patients with vasculitis, macroglobulinemia, or multiple myeloma in whom symptoms occur with exposure to cold.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Fasting specimen required: Overnight or minimum of 8 hours fasting.

Collect

Whole blood drawn in a prewarmed (37°C) syringe. Specimen may be drawn directly into a prewarmed lt. blue (sodium citrate) or black (sodium citrate).

Specimen Preparation

Maintain whole blood at 37°C from collection to transport; do not refrigerate or freeze at any time. Immediately after blood has been obtained, transfer specimen to a prewarmed blue (sodium citrate) or black (sodium citrate) (if not used for collection). Separate plasma from cells using a 37°C centrifuge, if possible. Transfer 3 mL plasma to an ARUP standard transport tube. (Min: 1 mL)

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated.

Unacceptable Conditions

Serum. Heparinized plasma. Grossly hemolyzed or lipemic specimens.

Remarks

Proper collection and transport of specimen is critical to the outcome of the assay. Quantities less than 3 mL may affect the sensitivity of the assay.

Stability

After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable

Methodology

Qualitative Cold Precipitation

Performed

Sun-Sat

Reported

3-5 days

Reference Interval

Negative at 72 hours.

Interpretive Data



Compliance Category

Standard

Note

Hotline History

N/A

CPT Codes

82585

Components

Component Test Code* Component Chart Name LOINC
0050190 Cryofibrinogen 29744-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • cryofibrinogen protein
  • Cryofibrinogen, Qualitative, Plasma
  • cryopreciptate
  • Cryoprotein
  • plasma cryofibrinogen
Cryofibrinogen