Cytomegalovirus Antibody, IgG
Ordering Recommendation

Detects past cytomegalovirus exposure. Not recommended for diagnosis in immunocompromised individuals.

Semi-Quantitative Chemiluminescent Immunoassay
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum Separator Tube (SST). 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated, or grossly hemolyzed specimens. 
Label specimens plainly as "acute" or "convalescent." 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles) 
Reference Interval
0.59 U/mL or less:Not Detected.
0.60-0.69 U/mL:Indeterminate - Repeat testing in 10-14 days may be helpful.
0.70 U/mL or greater:Detected.

Interpretive Data
In immunocompromised patients, CMV serology (IgG or IgM antibody titers) may not be reliable and may be misleading in the diagnosis of acute or reactivation CMV disease. The preferred method for diagnosis is culture of virus and/or demonstration of viral antigen in peripheral white cells (buffy coat), bronchoalveolar lavage (BAL) cells, or tissue biopsies.

This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0050165CMV Antibody IgG5124-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • CMV Ab, Quantitative
  • CMV Antibody
  • CMV IgG