Ordering Recommendation

Aids in diagnosis of hereditary angioedema and monitoring response to therapy.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Non-frozen specimens.

Remarks
Stability

After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun, Wed, Fri

Reported

1-4 days

Reference Interval

Test Number
Components
Reference Interval
  C-1-Esterase Inhib. Functional 41% or greater

Interpretive Data




Component
Interpretation
C-1 Esterase Inhibitor Functional 68% or greater     Normal
41-67%       Indeterminate
40% or less      Abnormal

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86161

Components

Component Test Code* Component Chart Name LOINC
0050141 C-1-Esterase Inhib. Functional 48494-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • C1 Esterase Inh,Func
  • C1 esterase inhibitor
  • C1 Inactivator
  • C1 INH functional
  • Functional Assay, Serum
  • Functional C1 Esterase
  • HAE
  • Hereditary Angioedema
C1-Esterase Inhibitor Functional