p53 with Interpretation by Immunohistochemistry
0049250
 
Immunohistochemistry Stain Form Recommended  (ARUP form #32978)Immunohistochemistry Stain Form Recommended (ARUP form #32978)
Ordering Recommendation
Mnemonic
P53 IP
Methodology
Immunohistochemistry
Performed
Mon-Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Tumor tissue.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin is preferred) and paraffin embed specimen. Protect paraffin block and / or slides from excessive heat. Transport tissue block or 5 unstained (3-5 micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min. 3 slides).If sending precut slides, do not oven bake.  
Storage/Transport Temperature
Room temperature or refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Paraffin block with no tumor tissue remaining; specimens fixed in B-5 or Bouin's fixative.  
Remarks
This test code includes pathologist interpretation. Include surgical pathology report. IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services at (800) 522-2787.  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
Negative : Less than 10% of nuclei stain
Positive: Greater than or equal to 10% of nuclei stain
Interpretive Data
Refer to report.
Note
CPT Code(s)
88360
Components
Component Test Code*Component Chart Name
0049251p53 Result
0049252p53 Percent of Tumor Cells Staining
2004523p53 Reference Number
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • p53 IHC
  • p53 IHC with interpretation
  • p53 immunostaining
  • p53 immunostaining with interpretation
  • Tumor Protein 53