Esterase Stain, Nonspecific
0049050
Ordering Recommendation
 
Mnemonic
EST-NS
Methodology
Cytochemical Stain
Performed
Mon-Fri
Reported
Within 5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
  • Anatomic Pathology Test Request Form Recommended (ARUP form #32960)
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) or green (sodium or lithium heparin). OR heparinized bone marrow aspirate.  
Specimen Preparation
Blood: Protect from light. Transport 5 mL whole blood AND 6 unfixed, air-dried, and unstained push smears made from the blood submitted. (Min: 1 mL AND 6 unfixed smears).
OR Bone Marrow: Protect from light.
Transport 1 mL heparinized aspirate AND 6 unfixed, air-dried, and unstained bone marrow aspirate smears. (Min: 0.5 mL AND 6 unfixed smears).  
Storage/Transport Temperature
Room temperature. Specimens should be received within 24 hours of collection; testing must be performed within 48 hours of collection.  
Unacceptable Conditions
Frozen specimens. Peripheral blood smears older than one year. Anticoagulated blood or bone marrow sent without well-prepared unfixed smears older than 48 hours.  
Remarks
  
Stability
Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable  
Reference Interval
Refer to report.  
Interpretive Data
Nonspecific Esterase stain (using alpha-naphthyl butyrate) is very useful in identifying monocytes found in acute monocytic leukemia (AML) types M4 and M5.  
Note
 
CPT Code(s)
88319
Components
Component Test Code*Component Chart Name
0049050Esterase Stain, Nonspecific
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Non-Specific Esterase
  • NSE
  • NSE Butyrate