Myeloperoxidase Stain
Ordering Recommendation
Determine myeloid lineage in AML per WHO classification. Less sensitive and specific than flow cytometry immunophenotype.
New York DOH Approval Status
Specimen Required
Lavender (EDTA) or green (sodium or lithium heparin) or heparinized aspirate of bone marrow.
Transport 6 unfixed, air-dried, and unstained push smears AND 5 mL whole blood (smears should be made from the blood submitted). OR 6 unfixed, air-dried, and unstained bone marrow aspirate smears.
Room temperature. Testing must be performed within 48 hours of collection.
Frozen specimens. Peripheral blood smears older than one week. Anticoagulated blood or bone marrow sent without well-prepared unfixed smears if greater than 48 hours old.
Ambient: 24 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Methodology
Cytochemical Stain
Performed
Mon-Fri
Reported
1-5 days
Reference Interval
Interpretive Data
Refer to report.
Standard
Note
Hotline History
CPT Codes
88319
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0049030 | Myeloperoxidase Stain | 32817-9 |
Aliases
- MPO
- MPO Stain
- Peroxidase Stain