B-Type Natriuretic Peptide
Ordering Recommendation

Aids in diagnosis, prognosis, and management of acute and chronic heart failure.

Quantitative Chemiluminescent Immunoassay
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Time SensitiveTime Sensitive
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Lavender (EDTA) or pink (K2EDTA). 
Specimen Preparation
Separate plasma from cells within 2 hours of collection. Transfer 2 mL plasma to an ARUP Standard Transport Tube and freeze within 4 hours of collection. (Min: 0.5 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Frozen whole blood. Specimens collected in non-EDTA tubes. Specimens frozen in separator tube.  Specimen exposed to repeated freeze/thaw cycles. Refrigerated or room temperature specimens more than 4 hours old. Hemolyzed specimens. 
After separation from cells: Ambient: 4 hours; Refrigerated: 4 hours; Frozen: 4 months 
Reference Interval
Refer to Interpretive Data.
Interpretive Data
A cutoff of 100 pg/mL has been demonstrated to provide the maximal combination of sensitivity, specificity, and negative predictive value for contributing to the diagnosis of congestive heart failure (CHF). A BNP value greater than 100 pg/mL is consistent with a diagnosis of CHF in the appropriate clinical setting. False-positive results are more common in females greater than 75 years of age. Blood concentrations of natriuretic peptides may also be elevated in patients with myocardial infarction and in patients who are candidates for or are undergoing renal dialysis.

Component Test Code*Component Chart NameLOINC
0030191B-Type Natriuretic Peptide30934-4
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  • BNP
  • BNP (Brain Natriuretic Peptide)
  • Brain Natriuretic Peptide
  • Brain Type Natriuretic Peptide
  • Natriuretic Peptide