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Macroprolactin
Ordering Recommendation
New York DOH Approval Status
Specimen Required
Serum separator tube or plasma separator tube. Also acceptable: Lithium heparin or EDTA plasma.
Allow specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Frozen.
After separation from cells: Ambient: 8 hours; Refrigerated: 7 days; Frozen: 1 month
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun
Reported
1-8 days
Reference Interval
| Test Number |
Components |
Reference Interval |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Monomeric Prolactin |
|
||||||||||
| Monomeric Prolactin Percent | Greater than 50% | ||||||||||
| Prolactin |
|
Interpretive Data
If the % Monomeric Prolactin is 40-50%, then the result is indeterminate for macroprolactin. If the % Monomeric Prolactin is less than 40%, then this indicates the presence of macroprolactin. A Monomeric Prolactin result above the upper reference limit is consistent with hyperprolactinemia.
Monomeric Prolactin was determined by PEG precipitation. Macroprolactin is precipitated by PEG and is not measured.
Modified FDA
Note
Hotline History
CPT Codes
84146 x2
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020766 | Monomeric Prolactin | 42607-2 |
| 0020767 | Monomeric Prolactin Percent | 50366-4 |
| 0070115 | Prolactin | 20568-2 |
Aliases
- Macroprolactin by PEG
- Macroprolactin, Serum
- PRL (Prolactin)
- Prolactin (PRL)
- Prolactin, Macro
