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Osteocalcin by Electrochemiluminescent Immunoassay
0020728
Ordering Recommendation
Mnemonic
OSTEO NMID
Methodology
Quantitative Electrochemiluminescent Immunoassay
Performed
Tue-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin). 
Specimen Preparation
Allow serum tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Hemolyzed specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 3 months 
Reference Interval
Age
Male
Female
6 months-6 years39-121 ng/mL44-130 ng/mL
7-9 years66-182 ng/mL73-206 ng/mL
10-12 years85-232 ng/mL77-262 ng/mL
13-15 years70-336 ng/mL33-222 ng/mL
16-17 years43-237 ng/mL24-99 ng/mL
18 years and older11-50 ng/mL11-50 ng/mL

Interpretive Data
In patients with renal failure the osteocalcin result can be elevated, both directly, due to impaired clearance, and indirectly, due to renal osteodystrophy.

Components
Component Test Code*Component Chart NameLOINC
0020728Osteocalcin by ECIA2697-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • BGLAP
  • bone gamma-carboxyglutamic acid-containing protein
  • N-MID osteocalcin
  • Osteocalcin
  • Osteocalcin (OCN)